About BPepAMPdb

Antimicrobial peptides (AMPs; also called Nature's antibioitics, 5–100 amino acid residues) are produced by most organisms as an innate immune response against microbes (World Health Organization, 2014). From time immemorial, black pepper has traditionally been used for the treatment of various diseases due to its antimicrobial, anti-inflammatory, antioxidant and anti-cancerous properties along with its wider applications and significance in dietary, nutrition, medicine, preservative, perfumery, insecticide and agricultural field (Hu et al., 2015; Gulcin, 2005; Raja and Sethuraman, 2008; Vijayan and Thampuran, 2000) making it a potent source for antimicrobial peptides that can combat against disease-causing pathogens. It is found to exhibit excellent antimicrobial activity with inhibitory effects against Gram-positive and Gram-negative bacteria (Zou et al. 2015). Their potent activity has led to strong interest in these molecules as targets for pharmaceutical research. This database provides comprehensive functional analyses for AMPs based on the large-scale black pepper proteome data and a downloadable package to discover known and novel AMPs on chromosome level. A total of 43,759 AMP sequence segments have been predicted from black pepper peptides and were found functionally associated with 10,935 unique genes retrieved from their respective gene ids obtained from the gtf file available online. The chromosome number, genomic location of AMPs, their associated gene ids and functional properties were cataloged in the database.